Development and evaluation of state-specific landscape data sets for multimedia source-to-dose models

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The specific aims of this study are (i) to develop for the CalTOX multimedia exposure
model landscape data sets for each state in and several regions of the US and (ii) use
these data sets to explore the regional variation of risk screening calculations. We
develop and evaluate forty-eight state-specific and nine region-specific landscape data
sets for use in calculating toxic equivalency potentials (TEPs). TEPs address the
information needs of risk management actions that require the comparison and
aggregation of releases of several chemicals to a number of environmental
compartments. We use state- and region-specific landscape data sets to calculate TEPs
for releases to both air and water among a large set of chemically hazardous agents.
We compare the TEPs calculated among states having significantly different landscape
properties. The purpose of this exercise is to evaluate the extent to which TEPs will
vary when applied in different US states or geographic regions. This exercise is also
used to explore the premise that a single default US landscape data set is sufficient for
making many kinds of LCIA classification. 278 chemicals are used in the analysis. Of
these, 230 are on the TRI list, 123 have carcinogen potencies, and 244 have non-cancer
allowable daily intakes. The results of the comparison suggest that TEPs can be reliably
derived with a single default US landscape data set. As a result, state-specific TEP
values may not be needed for assessments within the conterminous US.

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